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Global Research & Development of Novel Nano-Particle Medicine Targeting Monocytes/Macrophages Against Retinal Degeneration
About This Project
- Japan Grant Number
- JP22KK0136 (JGN)
- Funding Program
- Grants-in-Aid for Scientific Research
- Funding Organization
- Japan Society for the Promotion of Science
Kakenhi Information
- Project/Area Number
- 22KK0136
- Research Category
- Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Allocation Type
-
- Multi-year Fund
- Review Section / Research Field
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- Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
-
- Kyushu University
- Project Period (FY)
- 2022-10-07 〜 2026-03-31
- Project Status
- Granted
- Budget Amount*help
- 18,850,000 Yen (Direct Cost: 14,500,000 Yen Indirect Cost: 4,350,000 Yen)
Research Abstract
網膜変性は眼科領域の大きなアンメットニーズであり、加齢黄斑変性（Age-related macular degeneration：AMD）を含む多くの患者に高度の視力障害をもたらす。申請者はこれまでに神経炎症に着目して研究を進め、末梢血単球由来のマクロファージが網膜変性を促進するという新しいメカニズムを提唱してきた。このユニークなコンセプトを国際的に確立するために、このような網膜変性に伴う単球／マクロファージの変化が、人種や疾病を超えて起こっているかシングルセルレベルで解析する。また世界の失明原因の主因をなすAMDを対象として、抗炎症ナノ粒子薬のグローバル開発に取り組む。
Details 詳細情報について
-
- CRID
- 1040575263320978304
-
- Text Lang
- ja
-
- Data Source
-
- KAKEN