Understanding the efficacy of therapeutic antibodies through their interaction with cellular receptors.

About this project

Japan Grant Number
JP20H03228
Funding Program
Grants-in-Aid for Scientific Research
Funding organization
Japan Society for the Promotion of Science
Project/Area Number
20H03228
Research Category
Grant-in-Aid for Scientific Research (B)
Allocation Type
  • Single-year Grants
Review Section / Research Field
  • Basic Section 43040:Biophysics-related
Research Institution
  • Kyushu University
Project Period (FY)
2020-04-01 〜 2023-03-31
Project Status
Completed
Budget Amount*help
17,940,000 Yen (Direct Cost: 13,800,000 Yen Indirect Cost: 4,140,000 Yen)

Research Abstract

Therapeutic antibodies are improving human healthcare. To improve their efficacy and safety we need to understand how they work in a more precise manner. The binding of antibodies to Fc receptors starts a strong cellular response. We aim to understand how that happens at the molecular level.

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