Elucidating plasma effect on structural modification of antioxidant enzymes: Combined experimental and computational
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- Attri Pankaj
- Principal Investigator
- 九州大学
About this project
- Japan Grant Number
- JP20K14454
- Funding Program
- Grants-in-Aid for Scientific Research
- Funding organization
- Japan Society for the Promotion of Science
- Project/Area Number
- 20K14454
- Research Category
- Grant-in-Aid for Early-Career Scientists
- Allocation Type
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- Multi-year Fund
- Review Section / Research Field
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- Basic Section 14030:Applied plasma science-related
- Research Institution
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- Kyushu University
- Project Period (FY)
- 2020-04-01 〜 2023-03-31
- Project Status
- Discontinued
- Budget Amount*help
- 4,290,000 Yen (Direct Cost: 3,300,000 Yen Indirect Cost: 990,000 Yen)
Research Abstract
The conventional cancer therapies lack selectivity, and resistance to the treatment while plasma-mediated apoptosis induction acts selectively on tumor cells. However, the latest plasma oncology studies reveal that selectivity is not observed for all cancer cell lines. This may be due to the elevated levels of antioxidant enzymes in some cancer cells. Therefore, in this project, we will study the effect of cold atmospheric plasma on the structure and activity of antioxidant enzymes. Later, we will use this information to improve the efficiency and selectivity of the plasma treatment.
Keywords
Details 詳細情報について
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- CRID
- 1040848250657599104
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- Text Lang
- ja
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- Data Source
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- KAKEN