新規病態:HTLV-1陽性HRS細胞を伴う成人T細胞白血病/リンパ腫の統合的解析

About This Project

Japan Grant Number
JP23K27384 (JGN)
Funding Program
Grants-in-Aid for Scientific Research
Funding Organization
Japan Society for the Promotion of Science

Kakenhi Information

Project/Area Number
23K27384
Research Category
Grant-in-Aid for Scientific Research (B)
Allocation Type
  • Multi-year Fund
  • Single-year Grants
Review Section / Research Field
  • Basic Section 49020:Human pathology-related
Research Institution
  • Nagoya University
Project Period (FY)
2023-04-01 〜 2027-03-31
Project Status
Granted
Budget Amount*help
18,460,000 Yen (Direct Cost: 14,200,000 Yen Indirect Cost: 4,260,000 Yen)

Research Abstract

申請者らが同定したHTLV-1関連の新規病態である Adult T-cell leukemia/lymphoma with HTLV-1 infected HRS-like cells (ATLL-HH)に関し て、腫瘍細胞及び腫瘍微小環境の両面から詳細な解析を行い、ATLL、CHLとの差異を明らかにする。具体的には臨床病理学的特徴の把握、網羅 的遺伝子解析、シングルセル解析を組み合わせて解析し、ひいてはATLL-HHの診断、治療の向上につなげることを目的とする。

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