EFFECTS OF INTRAVESICAL TREATMENT OF BLADDER TUMORS WITH MITOMYCIN C

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Other Title
  • 膀胱腫瘍にたいするマイトマイシンCの膀胱内注入療法の検討
  • ボウコウ シュヨウ ニ タイスル マイトマイシン C ノ ボウコウ ナイ チュウニュウ リョウホウ ノ ケントウ

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Description

Intracavitary treatment with Mitomycin C (MMC) has been attempted on 32 cases of urinary bladder tumors and the results were as follows. 1. Complete disappearance of tumors was found in 11 out of 18 cases of papilloma and grade 1 of transitional cell carcinoma. On the other hand, in transitional cell carcinoma of grade 2, 3, 4, only 3 cases responded out of 14 cases. The result of clinical trial was that this treatment was more effective against low grade and small tumors. 2. Transmission of MMC into blood was very little. It'll explain the fact that serious side reactions of this treatment are very rare. 3. About the doses of MMC and frequency of this treatment, we suggest that trial of 20 mg of MMC twice a day and duration of 20 days are most satisfactory and effective.

Journal

  • Hinyokika Kiyo

    Hinyokika Kiyo 20 (1), 33-38, 1974-01

    京都大学医学部泌尿器科学教室

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