Leiomyosarcoma of the Kidney with Tumor Thrombus to the Inferior Vena Cava

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  • Kato, Taigo
    The Departments of Specific Organ Regulation (Urology), Osaka University Graduate School of Medicine
  • Nakai, Yasutomo
    The Departments of Specific Organ Regulation (Urology), Osaka University Graduate School of Medicine
  • Miyagawa, Yasushi
    The Departments of Specific Organ Regulation (Urology), Osaka University Graduate School of Medicine
  • Uesaka, Yuka
    The Departments of Specific Organ Regulation (Urology), Osaka University Graduate School of Medicine
  • Takao, Tetsuya
    The Departments of Specific Organ Regulation (Urology), Osaka University Graduate School of Medicine
  • Nonomura, Norio
    The Departments of Specific Organ Regulation (Urology), Osaka University Graduate School of Medicine
  • Okuyama, Akihiko
    The Departments of Specific Organ Regulation (Urology), Osaka University Graduate School of Medicine

Bibliographic Information

Other Title
  • 下大静脈腫瘍血栓を伴った腎平滑筋肉腫の1例
  • カ ダイ ジョウミャク シュヨウ ケッセン オ トモナッタ ジンヘイカツキン ニクシュ ノ 1レイ

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Abstract

A 76-year-old female presented with edema in the bilateral lower legs and computed tomography (CT) subsequently revealed a tumor under the right side of the kidney that extended to the inferior vena cava. Under suspicion of a right renal sarcoma or malignant teratoma, we performed a right nephrectomy and tumor thrombectomy. Histopathological features of the resected specimen were compatible with a leiomyosarcoma originating from either extrarenal blood vessels or muscle fibers of the renal pelvis. Immunohistological findings showed that the tumor cells were spindle-shaped, arranged in bundles, and stained positive for α-smooth muscle actin and desmin. The patient was free from recurrence 10 months after surgery. The prognosis of patients with a renal leiomyosarcoma with venous thrombus has been considered to be poor. Herein, we provide details of our case and conclude that radical tumor resection is necessary for a long-term cure.

Journal

  • Hinyokika Kiyo

    Hinyokika Kiyo 56 (12), 687-690, 2010-12

    泌尿器科紀要刊行会

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