MRIによる骨強度評価の基礎的検討 : 骨密度減少に伴うMR信号の変化

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  • MRI ニ ヨル ホネ キョウド ヒョウカ ノ キソテキ ケントウ コツミツド ゲンショウ ニ トモナウ MR シンゴウ ノ ヘンカ
  • Evaluation of Bone Strength Using Clinical MR Imager

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The purpose of this study was to evaluate whether magnetic resonance imaging (MRI) is useful for estimating the bone strength of humans. A 1.5 tesla whole-body MR imager (SIGNA advantage; GE) was used. Thirty volunteers (9 men and 21 women ; age range 21-76 years, mean age±S.D. 47.4±19.4 years) were examined with both MRI and single photon absorptiometry (SPA). The values for T1, T2, and T2* obtained using MRI were compared with bone mineral density (BMD) determined by SPA method. We found strong correlation between BMD and T2* (γ = -0.934). There were also significant correlation between BMD and T2 (γ = 0.849) and fat suppressed T2 (γ = 0.855). The correlations between BMD and Tl and fat suppressed T1 were reasonable (γ = 0.697 and γ = 0.623, respectively). It is concluded that T2* obtained using MRI may be a useful diagnostic tool for patients with osteoporosis.

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