Immunohistochemistry of BMP-Induced Heterotopic Osteogenesis

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Previously, our research group reported that the third ossification mode, "transchondroid bone formation", was chiefly di splayed in the BMP-induced heterotopic bone formation model 1-3). In this present paper, I describe the following: the histopathological and immunohistochemical features of BMP-induced heterotopic osteogenesis model in mice in the early phase of osteogenesis; and the localization of typical matrix proteins of cartilage and bone - type I and type II collagen, osteocalcin, and osteopontin- especially in the "chondroid bone matrix". Furthermore, I describe the expression of TGF-β peptide and its mRNA.

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  • Journal of Hard Tissue Biology

    Journal of Hard Tissue Biology 10 (2), 73-76, 2001-11

    Society for Hard Tissue Regenerative Biology (硬組織再生生物学会)

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