書誌事項
- タイトル別名
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- マンセイ ケツエキ トウセキ カンジャ ニ オケル Cガタ カンエン ウイルス カンセン ノ サーベイランス
- Surveillance of Hepatitis C Virus Infection in Hemodialysis Patient
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説明
In Japan, the rate of hepatitis C Virus (HCV) infection among hemodialysis patients is high (12.1%) ; yet, early detection of HCV infection among these patients is limited because their AST/ALT increase is small, an index or a standardized surveillance method is unavailable, the measurement of HCV antibody varies among facilities, and the conventional HCV-RNA test is costly. We applied the public HCV surveillance method to hemodialysis patients and examined its effectiveness. A total of 1,077 hemodialysis patient (690 males, 387 female ; mean age 59.8 ± 12.8 years old ; dialysis history 9.1 ± 6.0 years) were included. The public HCV surveillance method included a combination of HCV antibody, HCV core antigen, and HCV-RNA tests. Using this method, we detected 151 (14%) HCV antibody-positive patients, of whom the antibody was high in 89, medium in 50, and low in 12 patients. The conventional method would require all HCV antibody positive patients (n = 151) to undergo HCV-RNA test ; however, we only required 27 patients to undergo HCV-RNA test. The 82.1% reduction in the requirement for further testing shows that our method is cost effective and efficient. The surveillance method should be introduced to help reduce infection in hemodialysis patients.
収録刊行物
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- 東京女子医科大学雑誌
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東京女子医科大学雑誌 76 (2), 92-97, 2006-02
東京女子医科大学学会
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詳細情報 詳細情報について
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- CRID
- 1050001336269844352
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- NII論文ID
- 110007525406
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- NII書誌ID
- AN00161368
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- ISSN
- 00409022
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- HANDLE
- 10470/27058
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- NDL書誌ID
- 7883773
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- 本文言語コード
- ja
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- 資料種別
- journal article
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- データソース種別
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- IRDB
- NDL
- CiNii Articles