Bibliographic Information
- Other Title
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- Nutritional science and mental health : antidepressant activity of food ingredients and its evaluation
- メンタル ヘルス オ ササエル エイヨウ カガク : ショクヒン セイブン ノ コウウツヨウ カッセイ ヒョウカ
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Abstract
Nowadays anti-stress effect of food ingredients attracts much attention from the standpoint of maintenance of mental health. Nevertheless, definitive evidence on the effect is very few in human studies. The University of Tokushima proceeded the21st -Century COE Program,“Human Nutrition Science on Stress Control”, from 2004 to 2008. In this program, we carried out the screening and evaluation of antidepressant-like effect of plant polyphenols. It is suggested that plant polyphenols are able to suppress brain mitochondrial monoamine oixidase-A(MAO-A)activity which is responsible for the serotonin metabolism in synapses. In addition, intake of quercetin, a representative plant polyphenol, seems to affect hypothalamus-pituitary gland-adrenal cortex axis(HPA axis)leading to the suppression of plasma cortisol. It is therefore likely that plant polyphenols act as anti-stress ingredients from foods to contribute metal health, although more studies including human trials are obviously required.
Journal
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- 四国医学雑誌
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四国医学雑誌 66 (5-6), 123-126, 2010-12-20
徳島医学会
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Details 詳細情報について
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- CRID
- 1050001337465100160
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- NII Article ID
- 120006361011
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- NII Book ID
- AN00102041
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- ISSN
- 00373699
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- NDL BIB ID
- 11000841
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- Text Lang
- ja
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- Article Type
- journal article
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- Data Source
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- IRDB
- NDL
- CiNii Articles