Bibliographic Information
- Other Title
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- クロレラからの血圧降下作用糖蛋白質の検索(農芸化学部門)
- クロレラ カラ ノ ケツアツ コウカ サヨウ トウ タンパクシツ ノ ケンサク
- Detection of antihypertensive glycoprotein from chlorella (Agricultural Chemistry)
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Abstract
The antihypertensive material was partially purified from chlorella. Cell wall of chlorella was destroyed with Dyno-mill. After defatted and decolored with cold aceton, water extract was obtained from chlorella by the extraction at 4℃ for 24 hours. 80% ethanol precipitate from water extract was fractionated by Bio-Gel P-60 gel filtration followed by DEAE-cellulose chromatatography. About 50mg of antihypertensive fraction D-II were obtained from 10g of chlorella. The molecular weight of fraction D-II was about 80,000 dalton. The blood pressure of spontaneously hypertensive rat (13 weeks of age) was decreased from 185 to 150mmHg, when fraction D-II was injected intraperitoneally at the concentration of 0.5mg/100g of body weight. Fraction D-II contained galactose, mannose and glucosamine. The contents of aspartic acid, glutamic acid, alanine and proline in fraction D-II were large.
Journal
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- The scientific reports of Kyoto Prefectural University. Agriculture
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The scientific reports of Kyoto Prefectural University. Agriculture 35 138-143, 1983-11-15
京都 : 京都府立大学学術報告委員会
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Details 詳細情報について
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- CRID
- 1050001337626897408
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- NII Article ID
- 110000057814
- 220000027927
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- NII Book ID
- AN00062275
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- NDL BIB ID
- 2974629
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- ISSN
- 00757373
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- Text Lang
- ja
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- Article Type
- departmental bulletin paper
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- Data Source
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- IRDB
- NDL
- CiNii Articles