ヒ素の急性中毒における解毒剤の効果について

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  • Treatment of Arsenic Poisoning with Heavy-Metal Antagonists in Mice

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Metal binding agents, 2,3-dimercaptosuccinic acid (DMSA) and 2,3-dimercapto-1-propanesulfonic acid, Na salt (DMPS) were studied on the effectiveness for treatment of arsenic poisoning in mice. All mice which were given a toxic dose of arsenic trioxide (0.2 mmol As/kg, s. c.) survived by the treatment immediately after arsenic, with either one of these two agents (0.4 mmol/kg,i.p.). DMPS showed also the therapeutic effects against the acute poisoning with sodium arsenate and sodium monomethylarsonic acid.

Journal

  • 松本歯学

    松本歯学 9 (1), 47-51, 1983-06-30

    松本歯科大学学会

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