がん薬物療法におけるポジトロンCT の役割

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  • The Role of Positron Emission Tomography on Cancer Chemotherapy
  • ガン ヤクブツ リョウホウ ニオケル ポジトロン CT ノ ヤクワリ

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Abstract : 　It is the most important to evaluate the efficacy of anti-cancer agents rapidly in planning the treatment for the individual patient. The development of positron emission tomography (PET) has made it possible to study the metabolism of cancer tissues visually and evaluate the efficacy of cancer chemotherapy more rapidly and exactly than morphological examinations. 2-deoxy-2-[~18 F]fluoro-D-glucose (FDG) is a tracer for glucose metabolism and widely used in cancer diagnosis. Some reports showed that FDG was very useful for the early evaluation of cancer chemotherapy and the prediction of prognosis in patients with breast cancer, lymphoma, colonic cancer and esophageal cancer. From this point of view, tracers for nucleic and amino acid metabolisms are also promising. PET will play the more and more important role on the evaluation of efficacy for cancer chemotherapy.　　Key words : cancer chemotherapy, Positron emission tomography (PET), 2-deoxy-2-[~18 F]fluoro-D-glucose (FDG), evaluation of the efficacy for cancer chemotherapy

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