Calixarene-based photoresponsive ion carrier for the control of Na+ flux across a lipid bilayer membrane by visible light

DOI 機関リポジトリ (HANDLE) HANDLE オープンアクセス

説明

A photoresponsive ion carrier based on calix[4]arene was synthesized for the control of Na+ flux across lipid bilayer membranes by visible light. Calix[4]arene was chosen as a basic skeleton of a photoresponsive ion carrier because its ether derivatives are known to act as Na+ ion carriers in lipid bilayer membranes. For the synthesis of a photoresponsive carrier, dimethylaminoazobenzene was introduced as a photochromic moiety to an ether derivative of p-tert-butylcalix[4]arene. The ion transport ability of the dimethylaminoazobenzene appended calix[4]arene was examined by using a voltage-clamp method. When the calix[4]arene derivative was incorporated into a planar lipid bilayer membrane which separated two chambers filled with 100 mM of NaCl solutions, membrane currents resulting from Na+ flux were observed under applying external voltages between two chambers. The concentration dependence of the calix[4]arene derivative on the membrane currents indicated the formation of a 1:1 complex with Na+ ions for the calix[4]arene-mediated ion transport across the lipid bilayer membrane. By using visible light (> 400 nm), Na+ flux across lipid bilayer membranes containing the dimethylaminoazobenzene appended calix[4]arene derivative could be controlled.

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詳細情報 詳細情報について

  • CRID
    1050001338982351616
  • NII論文ID
    120000969111
  • DOI
    10.1016/j.matlet.2006.05.064
  • HANDLE
    2115/17193
  • ISSN
    0167577X
  • 本文言語コード
    en
  • 資料種別
    journal article
  • データソース種別
    • IRDB
    • CiNii Articles
    • KAKEN
    • OpenAIRE

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