Copper-catalyzed stereoselective conjugate addition of alkylboranes to alkynoates
Abstract
A copper-catalyzed conjugate addition of alkylboron compounds (alkyl-9-BBN, prepared by hydroboration of alkenes with 9-BBN-H) to alkynoates to form beta-disubstituted acrylates is reported. The addition occurred in a formal syn-hydroalkylation mode. The syn stereoselectivity was excellent regardless of the substrate structure. A variety of functional groups were compatible with the conjugate addition.
Journal
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- Beilstein journal of organic chemistry
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Beilstein journal of organic chemistry 11 2444-2450, 2015-12-04
Beilstein-Institut
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Details 詳細情報について
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- CRID
- 1050001339019362560
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- NII Article ID
- 120005690892
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- HANDLE
- 2115/60521
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- ISSN
- 18605397
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- IRDB
- Crossref
- CiNii Articles
- KAKEN