Regeneration and atrophy of muscle tissues

IR Web Site

Bibliographic Information

Other Title
  • 筋組織の再生と委縮
  • 筋組織の再生と萎縮
  • キン ソシキ ノ サイセイ ト イシュク

Search this article

Description

Professor Dr. Ota, who is the Manager of department rehabilitation research center, stated on research directionality. We surveyed knowledge about muscular tissues of human body. A smooth muscle, cardiac muscle and striated muscle consisting of the human body show specific function and morphology. These constructing mechanisms are different in details, but all muscles show myofibril shortening is caused by the myosin filaments sliding past the actin thin filaments, with no change in the length of either type of filament. The reproduction abilities are low in these muscles. In mouse, there is a report on renew and regeneration of cardiac muscle fibers, recently. We hope a success that new myocardium derived from Embryonic stem cells (ESC) or Induced pluripotent stem cells (iPSC) is continued heartbeat in vivo. In addition, atrophy is seen in a striated muscle. It depends on lesion of musculo-skeletal or a neurologic system, and E3 ubiquitin ligase is accepted commonly in sarcoplasm of atrophic muscle. We expect the recovery of the patient, independence to a daily life, and improvement of the QOL by appropriate correspondences.

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top