Total Synthesis of Dictyodendrins A–F by the Gold‐Catalyzed Cascade Cyclization of Conjugated Diyne with Pyrrole
この論文をさがす
説明
The total synthesis of dictyodendrins A–F was achieved using the gold(I)-catalyzed annulation of a conjugated diyne with NBoc-pyrrole for direct construction of the pyrrolo[2, 3-c]carbazole scaffold. Late-stage functionalization of the resulting pyrrolo[2, 3-c]carbazole to introduce various substituents provided divergent access to dictyodendrins. Some dictyodendrin analogues exhibited inhibitory activities toward CDK2/CycA2 and GSK3.
収録刊行物
-
- Chemistry – A European Journal
-
Chemistry – A European Journal 26 (49), 11064-11064, 2020-09-01
Wiley
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1050010293153501568
-
- ISSN
- 15213765
- 09476539
-
- HANDLE
- 2433/268303
-
- Web Site
- https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchem.202001950
- https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.202001950
- https://onlinelibrary.wiley.com/doi/full-xml/10.1002/chem.202001950
- https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchem.202002563
- https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.202002563
- https://onlinelibrary.wiley.com/doi/full-xml/10.1002/chem.202002563
-
- 本文言語コード
- en
-
- 資料種別
- journal article
-
- データソース種別
-
- IRDB
- Crossref
- KAKEN
- OpenAIRE