[原著］腸管及び尿路からの病原性大腸菌の諸性状に関する検討

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  • Characterization of Entero- and Uro-Pathogenic Escherichia coli

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Fifty strains of diarrheagenic E. coli (isolated from human diarrheal stool specimens) and 49 strains of uropathogenic E. coli (from human infected urinary specimens) were characterized for their biological behaviors: 38.9% of the latter strains produced hemolysin, while only 10% of the former did so. Resistance to human serum was identified in approximately 20% of the two groups. However, high susceptibility to the bactericidal effect of human serum was more commonly observed in the diarrheagenic strains. Protease productivity, extracellular protein secretion, and presence of Type I pili were observed in an equivalent population of the two groups. In contrast, the presence of hemagglutinin other than Type I pili were observed in 45.9% , of diarrheagenic group compared to 23.1% of the uropathogenic group. SDS-PAGE profiles of whole cell lysates showed some differences in protein distribution between the two groups for some selected strains.

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