HER2陽性高齢者乳癌に対するAnthracycline系薬剤回避レジメンの忍容性と有効性についての検討

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  • HER2 ヨウセイ コウレイシャ ニュウガン ニ タイスル Anthracyclineケイ ヤクザイ カイヒ レジメン ノ ニンヨウセイ ト ユウコウセイ ニ ツイテ ノ ケントウ
  • Tolerability and efficacy of a chemotherapy regimen avoiding Anthracycline for HER 2 positive elderly and poor risked breast cancer patients
  • 高齢者乳癌に対するAnthracycline回避レジメン

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Tolerability and efficacy of chemotherapy avoiding anthracycline regimen were examined histologically in ER negative and HER２positive elderly and poor risked breast cancer patients because of serious toxicity of Anthracycline regimen. Neo-adjuvant chemotherapy with ４ to ６ courses of Paclitaxel with Trastuzumab was given to ６ patients, Pertuzumab was added in 2 cases to obtain complete response. Adverse events were controllable, the primary treatment was completed without reducing the dose of drugs（RDI was １００％）. Clinical CR rate was recognized in all ６ patients and pathological CR was proved in all of the operated５cases.

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