Clinical practice guideline for drug-induced kidney injury in Japan 2016: digest version
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説明
The definition of DKI is a new onset of kidney injury or the worsening of an existing kidney injury due to drug administration. DKI can be classified based on the mechanism of pathogenesis, as well as on the damaged segment of the kidney. The classification based on the mechanism of pathogenesis is as follows: (1) toxic kidney injury (direct toxicity); (2) acute interstitial nephritis (AIN) due to allergic mechanism (hypersensitivity and direct toxicity); (3) indirect toxicity, such as electrolyte abnormalities and decrease of renal blood flow; and (4) obstruction of urinary tract. The classification based on the damaged segment of kidney is as follows: (1) glomerular injury; (2) tubular injury; (3) interstitial injury; and (4) vascular injury. The criteria for diagnosis are as follows: (1) new onset of kidney injury after the start of the administration of the candidate agent and (2) improvement or stoppage of the progression of the kidney injury after the cessation of the candidate agent, and all other causes can be ruled out. The cornerstone of treatment is the identification and cessation of the candidate agent as soon as possible.
収録刊行物
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- Clinical and experimental nephrology
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Clinical and experimental nephrology 20 (6), 827-831, 2016-12
Springer published in cooperation with Japanese Society of Nephrology
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詳細情報 詳細情報について
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- CRID
- 1050282677602870528
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- NII論文ID
- 120007135282
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- NII書誌ID
- AA11126935
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- ISSN
- 14377799
- 13421751
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- HANDLE
- 2241/00144923
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- PubMed
- 27714545
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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