Clinical practice guideline for drug-induced kidney injury in Japan 2016: digest version

USUI Joichi, YAMAGATA Kunihiro, Imai Eri, Okuyama Hiroshi, Kajiyama Hiroshi, Kanamori Hiroshi, Kono Emiko, Sakai Yukinao, Sakai Norihiko, Sakamaki Yuichi, Taniguchi Yoshinori, Nakai Kentaro, Nishiwaki Hiroki, Hirata Sumio, Yamaya Hideki, Tsuruoka Shuichi, Terada Yoshio, Yokoyama Hitoshi, Wada Takashi, Narita Ichiei

doi:10.1007/s10157-016-1334-0

The definition of DKI is a new onset of kidney injury or the worsening of an existing kidney injury due to drug administration. DKI can be classified based on the mechanism of pathogenesis, as well as on the damaged segment of the kidney. The classification based on the mechanism of pathogenesis is as follows: (1) toxic kidney injury (direct toxicity); (2) acute interstitial nephritis (AIN) due to allergic mechanism (hypersensitivity and direct toxicity); (3) indirect toxicity, such as electrolyte abnormalities and decrease of renal blood flow; and (4) obstruction of urinary tract. The classification based on the damaged segment of kidney is as follows: (1) glomerular injury; (2) tubular injury; (3) interstitial injury; and (4) vascular injury. The criteria for diagnosis are as follows: (1) new onset of kidney injury after the start of the administration of the candidate agent and (2) improvement or stoppage of the progression of the kidney injury after the cessation of the candidate agent, and all other causes can be ruled out. The cornerstone of treatment is the identification and cessation of the candidate agent as soon as possible.

Clinical practice guideline for drug-induced kidney injury in Japan 2016: digest version

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収録刊行物

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Clinical practice guideline for drug-induced kidney injury in Japan 2016: digest version

この論文をさがす

説明

収録刊行物

被引用文献 (10)*注記

参考文献 (1)*注記

関連プロジェクト

キーワード

詳細情報 詳細情報について

書き出し

問題の指摘

詳細情報詳細情報について