Nucleophilic 5-endo-trig Cyclization of 3,3-Difluoroallylic Ketone Enolates: Synthesis of 5-Fluorinated 2-Alkylidene-2,3-dihydrofurans

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<jats:title>Abstract</jats:title><jats:p>The title substrates (I) and (III) undergo KH‐mediated intramolecular O‐alkenylation to produce fluorinated dihydrofurans bearing a (Z)‐exo‐alkylidene unit.</jats:p>

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  • Synlett

    Synlett 24 (1), 57-60, 2013-01

    Georg Thieme Verlag

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