The Connection between Taste Blindness and Expression of Taste Receptors

IR Web Site

Bibliographic Information

Other Title
  • 〔研究ノート〕味盲と味覚受容体発現との関連
  • ミモウ ト ミカク ジュヨウタイ ハツゲン ト ノ カンレン

Search this article

Abstract

The authors examined the association of the expression of taste receptors and taste blindness. Subjects were 21 female university students aged 19-21. They were tested for whether they could taste phenylthiocarbamide(PTC). Four students, or 19% of the subjects, turned out to have taste blindness where PTC is concerned. The cells in their foliate papillae were scraped between meals and were measured by RT-PCR(SCREP method). The patterns of expressions hTAS2Rs and T1R3 which are correlated with taste blindness were examined. On average, the 4 students expressed 3.25 varieties of taste receptors. Specifically, 3 students expressed hTAS2R3 which is an orphan receptor. But they did not express hTAS2R38 which is a PTC receptor. Drawing on these facts the authors suggest that hTAS2R3 might be related to bitter substances which hTAS2R38 is also related to, and that specifically hTAS2R3 might play an important role for PTC non-tasters in recognizing toxic substances which are bitter.

6

KJ00007959079

Journal

  • GAKUEN

    GAKUEN 842 36-40, 2010-12-01

    東京 : 光葉会

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top