Design of a measurement cell for low-frequency dielectric spectroscopy of biological cell suspensions

書誌事項

公開日
2011-08
資源種別
journal article
権利情報
  • © IOP Publishing 2011
  • This is not the published version. Please cite only the published version.
  • この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。
DOI
  • 10.1088/0957-0233/22/8/085801
公開者
IOP Publishing

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説明

Dielectric spectroscopy of biological cell suspensions has a serious problem at low frequencies, where electrode polarization (EP) effects mostly mask their dielectric spectra. This paper describes a new type of measurement cell capable of extending the available low-frequency region by shifting the EP effects toward low frequencies. Its effectiveness was evaluated by computer simulation and experimental measurement on suspensions of erythrocytes and ghosts (hypotonically lysed erythrocytes). The results showed that the available low-frequency region was extended about ten times as compared with a corresponding conventional measurement cell, and that the low-frequency dispersion (so-called α-dispersion) of ghost suspensions was definitely observed.

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