A novel detection technique of polyamide binding sites by photo-induced electron transfer in (Br)U substituted DNA
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- A, Saha
- Department of Science, Graduate School of Science, Kyoto University
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- F, Hashiya
- Department of Science, Graduate School of Science, Kyoto University
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- S, Kizaki
- Department of Science, Graduate School of Science, Kyoto University
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- S, Asamitsu
- Department of Science, Graduate School of Science, Kyoto University
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- K, Hashiya
- Department of Science, Graduate School of Science, Kyoto University
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- T, Bando
- Department of Science, Graduate School of Science, Kyoto University
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- H, Sugiyama
- Department of Science, Graduate School of Science, Kyoto University・Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University
Abstract
We report the photochemistry of (Br)U substituted DNA as a versatile platform to investigate the binding sites of pyrene conjugated pyrrole imidazole polyamides (PIPs). The results suggest that the approach can be used on a routine basis for the screening of polyamide binding sites.
Journal
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- Chemical communications(Cambridge, England)
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Chemical communications(Cambridge, England) 51 (77), 14485-14488, 2015-10-04
Royal Society of Chemistry (RSC)
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Details 詳細情報について
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- CRID
- 1050282810834197504
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- NII Article ID
- 120006462491
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- ISSN
- 13597345
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- HANDLE
- 2433/230919
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- IRDB
- CiNii Articles