皮膚発癌機構と分子標的治療薬

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  • キョウジュ シュウニン キネン コウエン ヒフハツガン キコウ ト ブンシ ヒョウテキ チリョウヤク
  • Molecular carcinogenesis of the skin for development of novel therapy
  • ヒフ ハツガン キコウ ト ブンシ ヒョウテキ チリョウヤク

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Abstract

Skin cancers are considered to develop through accumulations of genetic and/or epigenetic events in normal cells of the skin. Among them, we focus on common skin cancers, including squamous cell carcinoma and melanoma. Many important molecules have been found to be involved in molecular carcinogenesis of these disorders, and some drugs targeting those molecules have been already developed. We review the updates on molecular carcinogenesis with our current works.

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