Bibliographic Information
- Other Title
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- ニシノミズホ シカ リンショウ イガク ショウレイショウ ジュショウ ソウセツ エンショウ カンキョウ ニ ヨル シズイ サイボウ ノ カンサイボウカ : シズイ サイボウ ブンカ ニ アタエル シュヨウ エシ インシ(TNF-a)ノ エイキョウ
- Reprogramming of Human Dental Pulp Cells Mediated by Inflammatory Signals : Effects of TNF-α on Human Dental Pulp Cell Differentiation
- エンショウ カンキョウ ニヨル シズイ サイボウ ノ カンサイボウカ : シズイ サイボウ ブンカ ニ アタエル シュヨウ エシ インシ TNF-α ノ エイキョウ
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Description
During normal pulp tissue healing, inflammatory cytokines, such as tumor necrosis factoralpha (TNF-α) or interleukins, act in the initial 48 hours (inflammatory phase) and play important roles not only as chemo-attractants of inflammatory cells and stem/progenitor cells but also in inducing a cascade of reactions toward tissue regeneration or reparative dentin formation or both. Previous reports have shown that inflammatory cytokines regulate the differentiation capacity of dental pulp stem/progenitor cells (DPCs), but none has interrogated the impact of these cytokines on the stem cell phenotype of stem/progenitor cells. In this review, I would like to summarize about the effects of a short-term treatment with TNF-α on the stem cell phenotype and differentiation ability of human DPCs.
Journal
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- Journal of Oral Health and Biosciences
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Journal of Oral Health and Biosciences 28 (1), 1-7, 2015-07-10
四国歯学会
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Details 詳細情報について
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- CRID
- 1050282812441733248
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- NII Article ID
- 120005823517
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- NII Book ID
- AA12713630
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- ISSN
- 21887888
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- NDL BIB ID
- 027957696
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- Text Lang
- ja
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- Article Type
- journal article
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- Data Source
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- IRDB
- NDL
- CiNii Articles
- KAKEN