The sensitivity and specificity of a Japanese version of the Mini-Mental State Examination

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  • 日本語版MMSEの検出力と特異性について
  • ニホンゴバン MMSE ノ ケンシュツリョク ト トクイセイ ニ ツイテ

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In this study, we determine the sensitivity and specificity of a Japanese version of the Mini-Mental State Examination(MMSE)conceived by Koumi H(2000, 2004, 2008). When a cutoff score of 24/25 points was assumed for clinical patients(including patients with amnestic mild cognitive impairment(MCI)and probable Alzheimer's disease)and healthy elderly controls who had taken the MMSE, the sensitivity was found to be 0.837, and the specificity, 0.957. These sensitivity and specificity levels were considered to be sufficient for the MMSE to serve as a screening test to distinguish between clinical patients and healthy elderly controls. However, when the MMSE cutoff score for amnestic MCI patients and healthy elderly controls was assumed to be 26/27 points, the test was found to have a sensitivity of 0.889 and specificity of 0.739. These sensitivity and specificity levels were considered to be insufficient to support the use of MMSE as a screening test for distinguishing between amnestic MCI and healthy elderly controls. In this case, it was necessary to examine in detail the results of other cognitive functional tests in order to distinguish between amnestic MCI and healthy elderly controls.

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