Reduced contribution of hypertension to the risk of silent brain infarction in the elderly : a population-based study in Takahata, Japan

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  • 高齢者集団の無症候性脳梗塞で高血圧症のリスクが軽減する
  • コウレイシャ シュウダン ノ ムショウコウセイ ノウコウソク デ コウケツアツショウ ノ リスク ガ ケイゲン スル

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Abstract

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The prevalence of asymptomatic ischemic brain lesions among the healthy elderly is high. We present a population-based cross sectional study of 240 subjects aged 70 years old (the Takahata Study), in which we have investigated the contributions of hypertension and other cerebrovascular risk factors to silent brain infarctions (SBI) in the elderly people. Of the 240 study subjects, 217 (90.4%) had SBIs. Hypertension was not significantly associated with SBIs. Further, diabetes mellitus, hypercholesterolemia, habitual drinking or smoking were also not associated with SBIs. We concluded that aging may weaken the association of hypertension and other risk factors with asymptomatic ischemic brain lesions.

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