A case of pregnancy complicated by typhoid fever in which the qSOFA score was effective in the diagnosis of sepsis.

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  • qSOFA scoreが診断に有効であった敗血症を伴う腸チフス合併妊娠の一例

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Typhoid fever is a systemic infection caused by Salmonella typhi and is often associated with bacteraemia. Its symptoms are often nonspecific, such as fever and diarrhoea. Although rare, severe complications of typhoid fever such as intestinal haemorrhage and bowel perforation can contribute to maternal mortality. Here we report a case of pregnancy complicated by typhoid fever, in which the ‘Quick Sequential Organ Failure Assessment (q-SOFA) score’ useful for effective and prompt therapy by helping in the diagnosis of sepsis. A 35-year-old female presented to the emergency department of our hospital with continuous diarrhoea and pyrexia for 3 days at a gestational age of 17 weeks and 2 days. She had no history of overseas travel. Her q-SOFA score was 2, which indicated sepsis due to gastrointestinal infection; therefore, antibiotic administration was started. S. typhi was detected from the blood culture sample on day 5. Fever was reduced on day 6 and diarrhoea improved. The patient was discharged from the hospital on day 20. Selective caesarean section was performed for the previous caesarean section at 38 weeks and 3 days of gestation, and both the mother and child were doing well. To improve maternal mortality rate, serious infectious diseases, including the rare ones, should not be overlooked and prompt diagnosis and treatment should be performed using the q-SOFA score.

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