Molecular dynamics simulation studies on the binding of an antifreeze protein to an ice interface

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  • 不凍タンパク質の氷界面吸着に関する分子動力学シミュレーション研究
  • フトウタンパクシツ ノ コオリ カイメン キュウチャク ニ カンスル ブンシ ドウリキガク シミュレーション ケンキュウ

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Abstract

Ice growth inhibition by antifreeze proteins occurs when the proteins bind to ice interfaces. However, a fundamental question of why the proteins bind to the interfaces still remains unclear. This review presents recent molecular dynamics simulation studies on the binding of the proteins to the interfaces. We will discuss the thermodynamic stability of the binding conformations of the proteins at the interfaces.

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