Heterologous production of asperipin-2a: proposal for sequential oxidative macrocyclization by a fungi-specific DUF3328 oxidase
Bibliographic Information
- Other Title
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- Biomolecular chemistry heterologous production of asperipin-2a: proposal for sequential oxidative macrocyclization
Abstract
Asperipin-2a is a ribosomally synthesized and post-translationally modified peptide isolated from Asperigillus flavus. Herein, we report the heterologous production of asperipin-2a and determination of its absolute structure. Notably, the characteristic bicyclic structure was likely constructed by a single oxidase containing the DUF3328 domain.
Journal
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- Organic & biomolecular chemistry
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Organic & biomolecular chemistry 17 (1), 39-43, 2019-01-07
Royal Society of Chemistry
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Details 詳細情報について
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- CRID
- 1050282814246311808
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- NII Article ID
- 120006776812
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- ISSN
- 14770539
- 14770520
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- HANDLE
- 2115/76469
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- IRDB
- Crossref
- CiNii Articles
- KAKEN