アルツハイマー病の背景と発症 : ヒトマイクロバイオーム(細菌叢)との関連の視点から

機関リポジトリ オープンアクセス

書誌事項

タイトル別名
  • Alzheimer’s disease : Relationship between the Alzheimer’s disease and human microbiome

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説明

Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by memory and language disorder. The accumulation of senile plaques called β-amyloid and neurofibrillary tangles involving protein tau in the brains of AD patients have been considered as two hallmarks of AD. In AD, it is reported that accumulation of β-amyloid may be observed 25 years before onset, supporting early diagnosis and treatment by brain image analysis, because several techniques have recently been developed to detect β-amyloid and tau protein in brains of persons diagnosed with AD. AD patients are usually suffering from other diseases such as diabetes or periodontal disease, and there is accumulating data to show that these diseases associate with the human microbiome, such as gut and oral microbiota. In this report, the relation ship between AD and the human microbiome is reviewed.

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詳細情報 詳細情報について

  • CRID
    1050283687312882304
  • NII論文ID
    120006383842
  • ISSN
    21867755
  • Web Site
    https://ousar.lib.okayama-u.ac.jp/55649
  • 本文言語コード
    ja
  • 資料種別
    departmental bulletin paper
  • データソース種別
    • IRDB
    • CiNii Articles
    • KAKEN

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