小脳性運動失調を呈した甲状腺機能低下症の1例

IR

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  • A CASE OF HYPOTHYROIDISM WITH CEREBELLAR ATAXIA

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A case of a 65-old-male with cerebellar ataxia associated with hypothyroidism is described. His recovery course was monitored by equilibrium function tests and with an electro-nystagmograph. It took about 2 months for the blood thyroxine level to return to normal. Although optokinetic nystagmus (OKN) could not be elicited before medication, the patient improved both in OKN and in the equilibrium function test in accordance with normalization of the blood thyroxine level. In the thyrotropine releasing hormone (TRH) injection test, the square measure of sway of the center of gravity was approximately halved three minutes after injection, and this effect lasted about 70 minutes. This is the first objective follow-up study for cerebellar ataxia with hypothyroidism, and the result of the TRH injection test suggests that TRH could participate in cerebellar ataxia associated with primary hypothyroidism.

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