Two Cases of IgG4-Related Systemic Disease Arising from Urinary Tract

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  • Takata, Masayuki
    The Department of Nephrology and Urology, Japanese Fukui Red Cross Hospital
  • Miyoshi, Mitsuru
    The Department of Nephrology and Urology, Japanese Fukui Red Cross Hospital
  • Kohno, Masanori
    The Department of Nephrology and Urology, Japanese Fukui Red Cross Hospital
  • Ito, Masanori
    The Department of Nephrology and Urology, Japanese Fukui Red Cross Hospital
  • Komatsu, Kazuto
    The Department of Nephrology and Urology, Japanese Fukui Red Cross Hospital
  • Tsukahara, Kenji
    The Department of Nephrology and Urology, Japanese Fukui Red Cross Hospital

Bibliographic Information

Other Title
  • 尿路に発生したIgG4関連硬化性疾患の2例
  • ニョウロ ニ ハッセイ シタ IgG4 カンレン コウカセイ シッカン ノ 2レイ

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Abstract

Case 1 : The patient was a 68-year-old man. Abdominal computed tomography performed during hospitalization for the close observation of a pituitary gland tumor, showed a right renal mass. Percutaneus needle biopsy revealed IgG4-related disease of the kidney. Pituitary gland tumor biopsy also indicated that the lesion was associated with IgG4-related disease. The pancreas did not show abnormalities. The patient was treated with prednisolone, and both renal and pituitary lesions markedly decreased in size. Case 2 : the patient was an 80-year-old man. Right hydronephrosis was observed, and computed tomography showed a right pelvic tumor. Right renal pelvic tumor was diagnosed, and the patient underwent right nephroureterectomy. Pathological examination showed that this tumor was also associated with IgG4-related sclerotic disease. IgG4-related disease tends to occur in multiple organs. This condition should be considered when treating patients with multiple sclerotic diseases. However, in some patients, the disease may be localized to a single site. Further studies are required to elucidate the characteristics of IgG4-related disease.

Journal

  • Hinyokika Kiyo

    Hinyokika Kiyo 58 (11), 613-616, 2012-11

    泌尿器科紀要刊行会

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