HumanHealth and Active Oxygen

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  • 人の健康と活性酸素
  • ヒト ノ ケンコウ ト カッセイ サンソ

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Aerobic organisms had their birth on the earth two thousand five hundred million years ago. They produced the oxygen that is a by-product of photosynthesis. One part of the oxygen changed to form active oxygen, which is deeply involved in human health and disease. The active oxygen included superoxide, single oxygen, hydroxyl radical, hydrogen peroxide, ozone and lipid peroxide. Vitamin C, vitamin E, carotenoids, and polyphenols that are taken in from foods are antioxidants. Superoxide dismutase (SOD), catalase and glutathione peroxidase also are antioxidants and are enzymes produced in the living body. Some methods of measuring antioxidant activity are known. The cumene hydroperoxide/ hemoglobin .Emethylene blue (CHP/Hb ・ EMB) technique is one of these methods, and was developed by authors. In order to maintain health, risk factors of life-style related diseases, such as high levels of cholesterol, smoking and hypertension, should be avoided. These are related with oxidized LDL and nitrogen monoxide which are one kind of active oxygen. Furthermore, antioxidants should be consumed consciously from foods and beverages, and it is also important to maintain a high level of antioxidant enzyme activity by taking moderate exercise.

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