Ingestion of sugar-beet fiber prevents hypercholesterolemia induced by ovariectomy in rats

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This study examined the effects of feeding sugar-beet fiber (SBF), a highly fermentable dietary fiber, on serum total cholesterol levels and liver cholesterol contents using female Sprague-Dawley rats (8 weeks old) with or without ovariectomy (OVX). The rats in each group were fed a SBF (100g/kg diet) or SBF-free diet for 5 weeks. The serum total cholesterol levels were elevated after OVX compared with that in the intact rats, and this elevation was partially prevented by the SBF diet. There were no significant differences in the relative liver weight among the groups. The hepatic total cholesterol contents in the SBF group were significantly lower than that in the control group in OVX rats. In conclusion, ingestion of SBF lowered the hepatic cholesterol contents and partially prevented increasing in the serum total cholesterol levels in OVX rats.

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KJ00004724432

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