Bibliographic Information
- Other Title
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- 水溶性フラボノイド配糖体αG-ルチンの消化管吸収機構
- スイヨウセイ フラボノイド ハイトウタイ アルファ G ルチン ノ ショウカカン キュウシュウ キコウ
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Abstract
Flavonoids are polyphenols that are found in many foods and which function as antioxidants in the body. However, the mechanisms for absorption of polyphenolic compounds remain unclear. The recently-manufactured quercetin glycoside αG-rutin is a water-soluble glucose adduct of rutin (quercetin-3-β-glucosyl-rhamnose) and this compound is 1,000 times dissolubility is higher than rutin. This review describes how the intestinal absorption and metabolism of αG-rutin in vivo, in situ and in vitro. αG-rutin is transported through the intestinal mucosa both in vivo and in vitro, and demonstrated that a considerable proportion of the αG-rutin was absorbed as the intact glycoside via the paracellular pathway. In addition, αG-rutin is absorbed more efficiency than either quercetin or rutin and that a high plasma concentration can be maintained by supplying rutin αG-rutin in combination in in vivo study. Thus, αG-rutin will be an effective source of quercetin and expected to be beneficial as antioxidant for human health.
6
KJ00005073552
Journal
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- 藤女子大学紀要. 第Ⅱ部 = The bulletin of Fuji Women's College. Series Ⅱ / 紀要第Ⅱ部編集委員会 編
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藤女子大学紀要. 第Ⅱ部 = The bulletin of Fuji Women's College. Series Ⅱ / 紀要第Ⅱ部編集委員会 編 45 31-38, 2008-03-31
札幌 : 藤女子大学
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Details 詳細情報について
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- CRID
- 1050564287558683392
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- NII Article ID
- 110006979331
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- NII Book ID
- AA11520347
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- ISSN
- 13461389
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- NDL BIB ID
- 9487422
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- Text Lang
- ja
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- Article Type
- departmental bulletin paper
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- Data Source
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- IRDB
- NDL
- CiNii Articles