書誌事項
- タイトル別名
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- Trial of Dietary Therapy Using Polymeric Diet for 3 Cases of Ulcerative Colitis
- カイヨウセイ ダイチョウエン 3ショウレイ ニ タイスル ハン ショウカタイ エイヨウザイ オ モチイタ ショクジ リョウホウ ノ ココロミ
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The clinical effects of dietary therapy (DT) were investigated using a low-residue/low-fat diet for breakfast and lunch(1000Kcal and less for breakfast and lunch together) and a polymeric diet alone (400-800 Kcal using Clinimeal) for dinneron 3 cases of moderate UC (total colitis-type UC [case 1: 15-year-old male], left-sided colitis-type UC [case 2: 58-year-oldmale; case 3: 66-year-old female]). Results: Case 1: During the administration of salicylazosulfapyridine (SASP) 3 g/day in combination with a low-residue/low-fat diet, bloody diarrhea relapsed every 1 hour. SASP 3 g/day and DT were used in combination, and 5 days afterinitiation of DT administration, no blood was observed macroscopically in stool, and diarrhea had changed to muddystool. On day 8, the patient felt hunger. After 22 days of DT administration, Ulcerative Colitis Disease Activity Index(UCDAI) score was 11. About 3 months later, UCDAI score was 3. Case 2: During the administration of SASP 3 g/day incombination with a low-residue/low-fat diet, the second relapse of left-sided abdominal pain and bloody stool was noted. DT was initiated, along with the following: SASP 3 g/day alone for 25days, steroid drug 20 mg/day (rectal application)alone for 16 days, and SASP 1.5 g/day alone for 21 days. AT 1week after initiation of DT administration, the amount ofblood in stool was reduced and the patient felt hunger. On day 44 of DT administration, UCDAI score was 7. On day 112 ofDT administration, UCDAI score was 3. UCDAI score at third relapse was 7, but following Steronema enema once a day atbedtime in combination with DT administration for 11 days, and thereafter, with administration of a normal, low-residue/low-fat diet, UCDAI score was 2 one month later. Case 3: 3 days before visiting this clinic, the patient noted soft, bloodystool 4-5 times in the morning. DT administration was begun without use of drugs. The amount of blood in stool decreasedfrom day 1 of DT administration. UCDAI score on day 10 of DT administration was 8.Conclusion: It has been suggested that DT may attenuate inflammatory reaction.
収録刊行物
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- 鹿児島大学医学雑誌=Medical journal of Kagoshima University
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鹿児島大学医学雑誌=Medical journal of Kagoshima University 62 (1), 9-13, 2010-05
鹿児島大学
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詳細情報 詳細情報について
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- CRID
- 1050564288839821696
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- NII論文ID
- 40017207837
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- NII書誌ID
- AN00040104
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- ISSN
- 03685063
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- NDL書誌ID
- 10763286
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- 本文言語コード
- ja
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- 資料種別
- departmental bulletin paper
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- データソース種別
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- IRDB
- NDL
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