μオピオイド受容体の多様性

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タイトル別名
  • Variability of μ-Opioid Receptors
  • mオピオイド ジュヨウタイ ノ タヨウセイ

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説明

The μ-opioid receptors are target receptors for narcotic analgesics. Although there is critical variability on their pharmacological effects between narcotic analgesics, only one μ-opioid receptor（MOR-1）DNA has been cloned. After the cloning of MOR-1 cDNA, many exons have been identified in the MOR-1 gene. With many exons in their gene, the MOR-1 has synthesized with a large number of splice variants. In the present review, the splice variants of MOR-1 and the possible physiological functions for specific splice variants have been discussed.

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