Bephenium塩(Alcopar)による鉤虫集団駆虫成績

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タイトル別名
  • Bepheniumエン Alcopar ニ ヨル コウチュウ シュウダン クチュウ セイセキ
  • Mass Treatment of Hookworm Infection with Bephenium Hydroxynaphthoate (Alcopar)

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This study was carried out in rural areas in Nagasaki prefecture to investigate anthelmintic efficacy of Bephenium Hydroxynaphthoate (Alcopar) against hookworm infection. The result obtained were summarized as follows; 1) a) In the case of the treatment with 5.0g. Alcopar, 4(75%) of 5 treated (student) and 64(36.4%) of 176 treated (adult) were negative for ova three weeks after administration. b) In the case of the treatment with 2.5g. Alcopar, 26(76.5%) of 34 treated (student) and 7(33.3%) of 21 treated (adult) were negative. 2) In general, Alcopar showed a promising efficacy (80～100%) against Anchylostoma duodenale infection and a rather low efficacy (27.8～75%) in the percentage of negativity for ova in the treatment of Necator americanus infection. 3) Toxic signs due to this drug were headache, nausea, diarrohae etc. which were slight in intensity.

長崎大学風土病紀要 4(4), p.301-306, 1962

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