書誌事項
- タイトル別名
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- Physiological role in liver on uric acid metabolism in rats
- ニョウサン タイシャ ニ オケル カンゾウ ノ セイリテキ ヤクワリ
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The aim of the present study is to investigate the physiological role of the liver on uric acid metabolism in rats. We measured plasma uric acid levels in portal vein and hepatic vein in rats fed a standard diet or a high fat diet. The uric acid level of hepatic vain was lower than that of portal vain. This result showed that the liver was involved in uricolysis. In rats fed the high fat diet, the uric acid levels were elevated in both of portal and hepatic vains. The increase of visceral fats, which had caused by the high fat diets, would decrease a performance of uric acid metabolism in the liver. We also showed a significant positive correlation between serum uric acid level and abdominal circumference in human. In conclusion, our findings suggested that abstention from high fat diet and reduction of visceral fat are important for prevention of hyperuricemia.
収録刊行物
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- 県立広島大学人間文化学部紀要
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県立広島大学人間文化学部紀要 6 55-60, 2011-02
県立広島大学
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詳細情報 詳細情報について
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- CRID
- 1050578283038278272
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- NII論文ID
- 120005379062
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- NII書誌ID
- AA12116573
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- ISSN
- 21865590
- 13467816
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- NDL書誌ID
- 11059048
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- 本文言語コード
- ja
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- 資料種別
- departmental bulletin paper
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- データソース種別
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- IRDB
- NDL
- CiNii Articles