書誌事項
- タイトル別名
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- A Case of Multisystem Inflammatory Syndrome in Children (MIS-C) with Heart Failure due to Myocardial Damage
- シンキン ショウガイ ニ ヨリ シンフゼン オ テイシタ ショウニ タケイトウ エンショウセイ ショウコウグン(MIS-C)ノ 1レイ
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説明
Multisystem Inflammatory Syndrome in Children (MIS-C) is a new disease that develops after coronavirus disease 2019 (COVID-19) and is known to cause severe inflammation in multiple organs, gastrointestinal symptoms, respiratory distress, and shock. <br>The patient was an 8-year-old boy who developed MIS-C one month after COVID-19 and presented with left ventricular systolic dysfunction and hypotension. Prednisolone (PSL) and high-dose immunoglobulin therapy (IVIG) improved some symptoms and part of the laboratory findings, but ferritin and D-dimer remained elevated, suggesting a cytokine storm. After infliximab (IFX) administration, ferritin and D-dimer improved, suggesting that IFX may be useful in suppressing cytokines that were not suppressed by the combination of PSL and IVIG. NT-proBNP and troponin T were elevated the day before shock and decreased with improvement in left ventricular contractility. We suggest that measurement of NT-proBNP and troponin T help in early prediction of shock in MIS-C.
収録刊行物
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- 信州医学雑誌
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信州医学雑誌 71 (5), 283-290, 2023-10-10
信州医学会
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詳細情報 詳細情報について
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- CRID
- 1390298047029578240
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- NII書誌ID
- AN00120815
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- ISSN
- 18846580
- 00373826
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- HANDLE
- 10091/0002001725
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- NDL書誌ID
- 033132131
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- IRDB
- NDL
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- 抄録ライセンスフラグ
- 使用不可