脱神経により廃用性萎縮をきたしたラット骨格筋に対する培養筋芽細胞の移植

IR Web Site 22 References

Bibliographic Information

Other Title
  • ダツシンケイ ニ ヨリ ハイヨウセイ イシュク オ キタシタ ラット コッカクキン ニ タイスル バイヨウ キンガ サイボウ ノ イショク
  • datsushinkei ni yori haiyosei ishuku o kitashita ratto kokkakukin ni taisuru baiyo kinga saibo no ishoku
  • Myoblasts transplantation into denervated rat muscles

Search this article

Abstract

type:text

The purpose of this investigation is to observe whether cultured my oblasts take in denervated muscle and differentiate myofiber without reinnervation. Cultured myoblasts survived in not only intact muscle but also denervated muscle without reinnervation at 1 week after transplantation. The cells differentiated myofibers in both intact and denervated muscles at 2 weeks and 4 weeks after transplantation. The ratio of denervated muscle weight to intact muscle weight decreased from 1 week to 4 weeks after myoblasts transplantation, but the decrease is not significant for first 2 weeks. These data suggest that transplanted myoblasts could survive and differentiate myofibers in denervated muscle and myoblasts transplantation before reinnervation may prevent denervated muscle atrophy and improve muscle regeneration after nerve repair.

原著

Journal

  • 慶應医学

    慶應医学 83 (4), 251-255, 2006-12

    慶應医学会

References(22)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top