食道癌治療のパラダイムシフト

書誌事項

タイトル別名
  • ショクドウガン チリョウ ノ パラダイムシフト
  • shokudogan chiryo no paradaimushifuto
  • Paradigm shift in treatment for esophageal cancer

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抄録

type:text

Surgery has been taking the lead of treatment for esophageal cancer in Japan. Since the later of 1990 chemoradiotherapy for esophageal cancer patients has become popular as a non-surgical modality. First of all, chemoradiotherapy was applied to patients with highly advanced stage (T4, M1lym), who cannot be cured by surgery, and became the standard treatment modality for this stage. Then chemoradiotherapy has been applied to patients with early stage as a trial based on[he remarkable results in highly advanced stage. The result of the JCOG clinical trial showed the excellent survival equal to the result by surgery for the same stage. Therefore a randomized controlled trial comparing chemoradiotherapy and surgery for this stage is ready to start. Recently the group of active medical oncologists has been applying chemoradiotherapy to the middle stage patients(Stage IIIII), for which surgery is recognized internationally as the standard modality tor esophageal cancer patients. The paradigm shift from surgery Io nonsurgery in treatment for esophageal cancer induce a new surgical item, salvage surgery following the failure of chemoradiotherapy or the cancer recurrence.

綜説

収録刊行物

  • 慶應医学

    慶應医学 82 (2), 47-53, 2005-06

    慶應医学会

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