バルプロ酸ナトリウム徐放剤の大量服用による自殺の1剖検例

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  • ショウレイ ホウコク バルプロサン ナトリウムジョホウザイ ノ タイリョウ フクヨウ ニ ヨル ジサツ ノ 1 ボウケンレイ
  • An autopsy case of acute intoxication of sodium valproate sustained released preparation tablets
  • バルプロサン ナトリウム ジョホウザイ ノ タイリョウ フクヨウ ニヨル ジサツ ノ 1ボウケンレイ

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説明

A young woman with epilepsy was found dead on her bed. She sent e-mail to her lover to intent to suicide １７ hours before being found dead. On the bed side, empty PTP sheets of ２０２ sustained released preparation tablets containing ２００ mg sodium valproate were left. Many tablets and its capsules were found in stomach and intestine by autopsy. The blood concentration of sodium valproate was １２６３ μg／ml, therefore we diagnosed that she died of sodium valproate intoxication. This case is first autopsy case of sodium valproate intoxication reported in Japan. And we also discuss about sustained released preparation tablets.

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