Diboron-Catalyzed Dehydrative Amidation of Aromatic Carboxylic Acids with Amines


Tetrakis(dimethylamido)diboron and tetrahydroxydiboron are herein reported as new catalysts for the synthesis of aryl amides by catalytic condensation of aromatic carboxylic acids with amines. The developed protocol is both simple and highly efficient over a broad range of substrates. This method thus represents an attractive approach for the use of diboron catalysts in the synthesis of amides without having to resort to stoichiometric or additional dehydrating agents.


  • Organic Letters

    Organic Letters 20 (15), 4397-4400, 2018-08-03

    ACS Publications

Citations (14)*help

See more


See more

Related Projects

See more


Report a problem

Back to top