ビュルガー病の成因に関する患者・対照研究 : 成長期の身体状況との関連

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  • A Case-Control Study of Buerger's Disease-In Special Reference to the Physical Development during the Adolescent Stage

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A case-control study was conducted to identify the risk factors of Buerger's disease except for smoking. This study was carried out on the basis of a working hypothesis that the physical inactivity, debility and having diseases during the adolescent stage inhibit the development of arteries and predispose to Buerger's disease. Cases were 121 male patients who were receivers of national financial aids for the treatment of the disease in Niigata Prefecture. Controls were matched to the case by age (±5 years old), sex and the place of residence. Especially for the purpose of exclusion of the effect of smoking, a control for a case who had experience in smoking was also smoker. The results of statistical analyses among smokers were as follows; 1) Overweight at age of the entrance to junior high school was significantly associated with Buerger's disease. There were also dose-response relationships between the extent of body weight and Buerger's disease at the age of the entrance to junior and senior high schools. 2) Controls were engaged in physical exercises as an extracurricular activity in higher grades at a primary school.

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