バンチ症候群の臨床病理学的研究

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タイトル別名
  • パンチ症候群の臨床病理学的研究
  • パンチ ショウコウグン ノ リンショウ ビョウリガクテキ ケンキュウ
  • CLINICAL AND PATHOLOGICAL STUDY ON BANTI-SYNDROME.
  • 原著
  • Original Article

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In our department, we have experimented 62 cases of Banti-syndrome, which had been treated with splenectomy in past ten years. We pe.rformed the follow-up biopsies after the splenectomy on 17 cases among these 62 cases. In this paper, I report about the pathology of this syndrome with clinical and pathological examinations, mainly with histological findings of liver and spleen. Among these patients, more than half of the cases (33 patients) were in pre-menopausal multipara females. The histological findings of spleen were as follows : (1) Diffuse proliferation of reticulo-lymph cells, as initial findings. (2) "Pulpa hyperplasia" or sclerosed spleen which seemed to be in a course of progression or result of group (1). (3) "Sinus hyperplasia" which happened to be caused by unexpected shock to the spleen of group (1) and (2). These three groups seemed to correlate to the clinical findings as cause-result relation in the course of disease, such as hepato-splenomegaly, pancytopenia, hypochromic iron-deficiency anemia, hemolytic tendency, liver function disturbance and portal hypertension, respectively. It has been recognized that there had been no pathological improvement of the liver, and also no essential changes in the liver by splenectomy, according to the results of clinical examination including the liver biopsies which had been done half a year to 6 years after splenectomy.

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