エルゴチオネインとその生体内作用

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タイトル別名
  • Ergothioneine and its effects in vivo
  • エルゴチオネイン ト ソノ セイタイナイ サヨウ

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Ergothioneine（EGT）is a hydrophilic sulfur-containing amino acid and can directly remove reactive oxygen species. More than 100 years have passed since its discovery. Although EGT has a high antioxidant capacity, its role in vivo has not been clarified yet. EGT exists in the bodies of animals and plants, including humans, but animals cannot biosynthesize EGT themselves. Animals have an EGT transporter, which is expressed in organs that are exposed to strong oxidative stress. EGT transporter expresses not only plasma membrane but also mitochondria membrane and protects from oxidative stress. In recent years, it has been reported that EGT is effective against diseases such as neurodegenerative diseases, diabetes, and cancer. EGT is thought to be one of the most important small molecules that may be useful in the diagnosis and treatment of various diseases in the future.

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