書誌事項
- 公開日
- 2012-02
- 資源種別
- journal article
- 権利情報
-
- https://www.elsevier.com/tdm/userlicense/1.0/
- https://www.elsevier.com/legal/tdmrep-license
- DOI
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- 10.1016/j.coph.2011.10.020
- 公開者
- Elsevier BV
この論文をさがす
説明
The μ-opioid receptors mainly contribute to the control of pain transmission, while a number of splice variants may have different physiological roles. In fact, some μ-opioid receptor agonists show distinct antinociceptive properties probably mediated via splice variants insensitive to traditional μ-opioid receptor agonists. These atypical μ-opioid receptor agonists are extremely effective against morphine-resistant interactive pain and lack the psychological dependence liability. μ-Opioid receptor splice variants specific for these atypical agonists may be the target for better analgesics effective against morphine-resistant interactive pain and lacking psychological dependence liability.
収録刊行物
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- Current Opinion in Pharmacology
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Current Opinion in Pharmacology 12 (1), 87-91, 2012-02
Elsevier BV
